SARS-CoV-2 evolution in light of Omicron

Spring 2022

Rapid displacement of existing diversity by Omicron

Trevor Bedford, March 2022

SARS-CoV-2 evolution - multiple potential avenues

Trevor Bedford, March 2022

Currently unclear how common Omicron-like events will be

Trevor Bedford, March 2022

Tracking Omicron subvariants

Summer 2022

Rapid displacement of existing diversity by emerging variants

Trevor Bedford, July 2022

Cases and frequency data reveal overlapping epidemics

Trevor Bedford, July 2022

The rise of XBB

Winter 2022-2023

Convergent evolution

Pavitra Roychoudhury, Nov 2022

XBB - first major recombinant variant

Pavitra Roychoudhury, Jan 2022

Antigenic drift of XBB -> EG.5 (and others)

Summer 2023

Diversification and convergence within XBB

Trevor Bedford, May 2023

Convert evolution at 456L (and 455F) and the rise of EG.5

Trevor Bedford, Nov 2023

JN.1 the next saltation event

Winter 2023-2024

Divergent BA.2 sublineage noted (Fall 2023)

Pavitra Roychoudhury, Sept 2022

SARS-CoV-2 diversity (Jan 2024)

Trevor Bedford, March 2023

Rapid global sweep of JN.1

Trevor Bedford, March 2023

Diversification and drift of JN.1

Summer 2024

JN.1 diversity at S:456

nextstrain.org

JN.1 causing a slight increase in waste water

Cycle of drift (summer) larger leaps (winter)